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Fluconazole is an antifungal medication used in the treatment of several fungal infections. The drug is used orally and intravenously. Fluconazole widely distributes into body tissues, nails and fluids including saliva, sputum, vaginal secretions. Fluconazole does not undergo first pass metabolism and is excreted mostly in the urine and some in the feces. This drug can also be used in the pediatric population. Fluconazole works by altering the fungal cell membrane. It exerts its fungistatic effect by selectively inhibiting 14-alpha demethylase. This is a cytochrome P-450 enzyme that is necessary for synthesizing ergosterol, which is an important component of the fungal cell membrane. 14-alpha demethylase converts lanosterol to ergosterol. Without ergosterol, 14 alpha-methyl sterols increase which subsequently causes the fungal cell membrane to exhibit increased cellular permeability. This causes the components inside the cell to leak.

Other names for this medication:
Fluconazole, Diflucan, Afumix, Afungil, Batacan, Candidin, Diflazon, Difluzol, Difluzole, Dizole, Dofil, Duracan, Efac, Elazor, Exomax, Farzul, Fluc, Flucomed, Flucon, Fluconapen, Fluconazol, Flusenil, Flutec, Fluvin, Fluzol, Fluzole, Fluzone, Forcan, Govazol, Honguil, Ibarin, Kifluzol, Lavisa, Logican, Lucon, Medoflucon, Novacan, Omastin, Ozole, Ponaris, Rifagen, Sacona, Stabilanol, Syscan, Ticamet, Trican, Triflucan, Trizol, Uzol, Varmec, Zemyc, Zolax, Zoldicam, Zolen, Zoloder, Zucon,

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A D-lysergic acid-activating enzyme from the ergot fungus Claviceps purpurea was purified about 145-fold. Comment on: Choroidal thickness changes after dynamic exercise as measured by spectral-domain optical coherence tomography. Percutaneous Coronary Intervention With Bioresorbable Scaffolds in a Young Child.

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Prediction of tricyclic antidepressant response: a critical review. Intrapericardial denervation: radial artery blood flow and heart rate responses to LBNP. The effect of acute non-fatal haemorrhage on adrenocortical function.

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Depending on the immunogenicity of human tumors, COX-2 inhibition might be useful as adjuvant therapy for surgically resectable NSCLC. Obesity has been implicated in the etiology of postmenopausal breast cancer (PBC).

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Introduction: Investigation of supportive care needs of cancer patients is important to implement any supportive care programs. To classify bursting (the desired behavior), we use a simple cost function whose inputs are derived from the frequency content of the neural output. Intercropping also contributes to better nutrition of plants with Zn, P and K, most probably by affecting biological and chemical process in the rhizosphere.

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The thioalkylating agent N-ethylmaleimide (NEM) causes ouabain-insensitive K loss from human red blood cells. Complex biochemical mechanisms are being involved in oleaginous microorganisms during storage lipid and polysaccharide metabolism. As part of an examination of procedures for protein/lipid reconstitution we incubated solubilized cytochrome oxidase at different temperatures with preformed vesicles composed of saturated lipids. These results suggest that children aged less than 12 years and older children with normal vitamin E levels are especially unlikely to have low 25-OH vitamin D levels, and this measure can therefore be omitted. The restrictive concept of good health in patients with hypochondriasis.

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Further, a systematic change in stopover duration will result in a change in the probability of detecting individuals once, but also in the probability of detecting individuals on more than one sampling occasion. Only one person had a documented history of measles vaccination, a child who had received one dose of vaccine overseas.

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Factors influencing the distribution of tuberculosis cases in an inner London borough. FINE TISSUE AND SUBMICROSCOPIC DIFFERENTIATION OF CONNECTIVE TISSUE CHANGES DUE TO AGING AND DEGENERATION We conducted and analyzed a cross-sectional survey of non-Hispanic white and black students from four universities, exploring associations between verbal and nonverbal consent, contraceptive use and covariates.

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Chronic obstructive pulmonary disease (COPD) is one of the most debilitating somatic diseases, having anxiety and depression frequently as comorbidities. The surgery resulted in an abdominal wall defect measuring 223cm2, for the management of which direct closure was not possible. Regulation of the cell proliferation and migration as extra-pituitary functions of GnRH. The results also implied that miR-22-3p/miR-149-5p might exert anticancer effects in cases of long-term FA deficiency.

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After performing calibration experiment we found that the sample set chosen by this algorithm are equally representative to the original sample set and obtained almost the same precision compared to the original sample set when the two sample sets were individually calibrated. In view of these findings we suggest that tinidazole does not act directly on the primary EBV infection in vitro. Of these cases, 41 were performed using 3-mm CT slices and 15 were performed using 1-mm slices, enabling us to compare the accuracy of the system and the radiation exposure using the different slice thicknesses.

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Additionally, the 1-pK and 2-pK models predict different electrokinetic potentials in spite of very similar values of calculated surface charge and ion adsorption isotherms when the same value of outer-layer capacitance is assumed. We discuss the mechanisms involved in the development of pneumothorax in patients with lung cancer, the clinical significance of the association, and the recommended diagnostic approach and therapeutic guidelines. Magnitudes of published MIDs for fatigue PROMs vary considerably. Only CD patients have a significantly higher risk of developing GD than well-matched hospital controls. From the results, it was found that the textural properties, including the specific surface area and the pore volumes, were proportionally enhanced with increasing activation temperatures.

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Further characterization of signaling by one such cAMP-independent factor, TGFalpha, demonstrated that the mechanism, whereby it increased StAR expression and steroid synthesis, was dependent on de novo protein synthesis and mediated via activation of the EGF receptor. These highly active chemical attractants have been synthesized for some of the most important insect pests, including the boll weevil, gypsy moth, codling moth, tobacco budworm, European corn borer, and several bark beetles.

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Identification and characterization of early growth response 2, a zinc-finger transcription factor, as a p53-regulated proapoptotic gene. The results of this study suggest an enhanced release of nitric oxide in the early stages of diabetes, which is more evident in the untreated diabetic rats than the insulin treated, and appears to normalize as the duration of diabetes progresses. Socioeconomic impact of modern multidisciplinary management of retinoblastoma. An increased incidence of infections by Haemophilus influenzae type f (Hif) has recently been suggested, but such infections have mainly been regarded as opportunistic. Immunohistochemistry demonstrated the presence of antiangiogenic factors (PEDF, angiostatin, restin, and endostatin) and proangiogenic molecules (VEGF, bFGF, MMP-2, and MT1-MMP) in the cornea after wounding.

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Several recent studies have demonstrated that expression of the tumour-suppressor gene p53 increases within the nervous system after injury. In vivo experiments showed that sCT induced an increase in cGMP in human urine, which was rapid and short-lasting, being superimposable on the increase of urinary excretion of calcium and magnesium.

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The complexity and variability of the root canal system, together with the multi-species nature of biofilms, make disinfection of this system extremely challenging. Erratum to: Detoxifying Escherichia coli for endotoxin-free production of recombinant proteins. The C-H borylation reaction could be conducted on a gram scale, and with a bioactive molecule as a substrate, demonstrating its applicability to late-stage regioselective C-H borylation. Oesophageal cavernous haemangioma diagnosed histologically, not by endoscopic procedures.

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Furthermore, MUC3 mRNA is expressed in a differentiation dependent manner, as is the case for enterocytes. A combined high-voltage and scanning electron microscopic study of two types of sensory cells dissociated from the gastrodermis of Hydra. A FOLLOW-UP STUDY ON THE INFLUENCE OF INDIVIDUAL OPINION ON THE CONSTRUCTION OF AN ATTITUDE SCALE. High levels of serum sialyl Lewis(a) (sLea) are frequently found in cholangiocarcinoma (CCA) patients and have been suggested to be a serum marker for CCA. TTE was found more suitable for cardiac valves and septal defects because of the availability of flow imaging.

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During the course of cirrhosis, sinusoidal portal hypertension leads to splanchnic and systemic vasodilation, responsible for a reduction of effective arterial blood volume. Catatonic syndromes could accompany a variety of psychiatric and medical conditions. Neuronal degeneration in locus ceruleus and cortical correlates of Alzheimer disease. 50 years ago in CORR: Disability following crush fracture of the calcaneus. The cynomolgus monkey array and 12,613 probes were used in DNA microarray analysis, and the affected genes were categorized using gene ontology analysis.

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Macular hole can occur in Bietti crystalline dystrophy and the post-surgical outcome is good. Surgical Myectomy after Failed Ablation for Hypertrophic Obstructive Cardiomyopathy. Characterization of Myocardial Dysfunction in Fluid- and Catecholamine-Refractory Pediatric Septic Shock and Its Clinical Significance.

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Sensitive Aflatoxin B1 Determination Using a Magnetic Particles-Based Enzyme-Linked Immunosorbent Assay. The reproducibility of the pattern is excellent and requires relatively simple and noninvasive techniques. Our study demonstrates that faecal samples can be a useful source for the determination of kinship in a whole community.

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Etiology is unknown, connection between disturbances of serotonin metabolism and pathogenesis is postulated. In outer hair cells, IMPs of about 10 nm in diameter were seen on the P-face of the afferent postsynaptic membrane at a density of 3,000/microns 2. For the evaluation and assessment of cancer risk due to asbestos epidemiological studies have to be conducted.

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One patient died after surgery because of intracranial hemorrhage. All had full prescription drug coverage, including NSAIDs and selective COX-2 inhibitors. However, little is known about the factors that predispose individuals to the development of both anxiety disorders and nicotine use. Different factors are related to the absence of mental health problems of children working on the streets after enrollment in a two-year psychosocial program.

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To assess and compare the efficacy and toxicity of radiotherapy (RT) versus chemotherapy (CT) in patients with nodal and isolated nonnodal recurrence of ovarian cancer. We assessed engagement in premorbid leisure-time exercise among 102 drug naive PD patients who had been initially diagnosed at our hospital by dopamine transporter scanning. Thus, the long-term adhesive strength between bone and bone cement is decreased resulting in premature aseptic loosening. Results of investigations of fluorescent properties of a beta-substituted carbocyanine and its complexes with nucleic acids in comparison with those for the unsubstituted dye are presented.

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In this cohort study, data from ischemic stroke patients in Get With The Guidelines-Stroke linked to fee-for-service Medicare data were analyzed. Measuring oral health: does your treatment really make a difference. The authors describe effective surgical solution of the case by laparoscopy from a transabdominal approach. The first aim of the study was to examine the effects of carbamazepine, a standard antimanic treatment, on the stress resilience of sensitized rats, to further characterize morphine sensitization as a model of manic symptom. The number of capillaries per cell was doubled (as evaluated on semithin sections).

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Unexpectedly, Amerindian mitochondrial ancestry was the highest in the Northeastern region overall, followed by African, European and non-Amerindian Asian, unlike previous results for this region. Transthoracic Biopsy Causes Massive Subcutaneous Emphysema in a Low Risk Patient. These observations indicate that the intensity of the gallium uptake reflects mainly the degree of granuloma formation in the lung, and gallium scintigraphy may be an indicator for predicting the degree of activity of pulmonary sarcoidosis. Modulation of an AMPA-like glutamate receptor (SqGluR) gating by L- and D-aspartic acids.

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A type I combi-targeting approach for the design of molecules with enhanced potency against BRCA1/2 mutant- and O6-methylguanine-DNA methyltransferase (mgmt)- expressing tumour cells. Cytologic diagnosis using needle aspiration of basal cell monomorphic adenoma, pleomorphic adenoma and cystic adenoid carcinoma of the salivary glands (differential diagnosis and prognostic and therapeutic implications) To investigate the association of endometriosis with estrogen receptor alpha (ER alpha) and cytochrome P450c17alpha (CYP17) gene polymorphisms in light of the fact that estrogen plays a role in the pathogenesis of endometriosis and the CYP17 enzyme is involved with estrogen biosynthesis. The present results suggest that a decrease in GABAB neurotransmission in the ventral tegmental area, which may be produced via inhibition of a tonic GABAergic input by morphine, may be involved in the expression of the rewarding effect of morphine.

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Free floating right heart thrombus is a rare phenomenon in the context of acute pulmonary embolism and it is associated with a poor outcome. To identify differentially expressed regulatory ncRNAs involved in EBV infection, a specialized cDNA library, enriched for ncRNAs derived from EBV-infected cells, was subjected to deep-sequencing.

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Notification that new names and new combinations have appeared in volume 60, part 8, of the IJSEM. This study assesses the safety and tolerability of a continuous regimen of sorafenib combined with TACE.

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A newly discovered T cell subset that helps B cells is expanded in joints of rheumatoid arthritis patients. Glossopharyngeal neuralgia is characterized by intermittent shooting sharp pain in the jaw, throat, tongue, and ear.

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Immunohistochemical staining was employed to analyze for eight biomarkers: cytokeratin 5/6 (CK5/6), epidermal growth factor receptor (EGFR), p53, Ki-67 antigen (Ki-67), E-cadherin, N-cadherin, topoisomerase 2 alpha (TOP2A) and B-cell lymphoma 2 (BCL-2), which were then correlated with the nuclear grade (NG), tumor diameter, and the presence/absence of lymph node metastasis, distant recurrence and lymphatic infiltration. Obesity is a state of subclinical inflammation resulting in loss of function of insulin receptors and decreased insulin sensitivity.

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Other pilot trials should explore possible areas of psychotropic action of levetiracetam prior to the conduct of more controlled clinical trials. Though the drug potentiated phasic contraction, it did not potentiate tonic component of Ca contracture. Kinetic assessment of urea, the main end product of protein metabolism, could serve to assess protein catabolism in dogs with chronic kidney disease (CKD). Patients were grouped according to their fracture location, determined from radiographs of the anteroposterior pelvis.

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Comparison of two methods for measuring 25-OH vitamin D in the follow-up of patients after bilio-pancreatic diversion bariatric surgery. The functionalized colloidal solutions prepared are hopeful of use as fluorescence probes in biological staining and diagnostics.

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In some cases a doughnut-shaped sheet of silastic was inserted between the horns, and in most cases the chorioallantoic membranes of the respective fetuses were sutured to one another prior to suturing the uterine walls. The pathogenesis of elevated intracranial pressure in children and adolescents with craniovertebral pathology uses their previous model of bargaining with outside options to explain fairness and other features of human sociality. Community ecology of metazoan parasites of the later juvenile common snook Centropomus undecimalis (Osteichthyes: Centropomidae) from the coastal zone of the State of RIo de Janeiro, Brazil. It also explores the perceptions of stakeholders of the prenatal care benefit package in order to understand the strengths and weaknesses of the approach in the context of rural China and to draw lessons from early implementation.

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Prdx6 in hLECs was hyperoxidized after exposure to high amounts of UV-B. Strain M12 is also a potential producer of phytases, enzymes useful in food processing and agriculture. In the majority of these, the causative proteins share no homology to other known proteins, or to each other apart from the polyglutamine tract. Chemotherapeutic Strategies for Peritoneal Dissemination of Gastric Cancer

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striatellus distributed uniformly along the whole genome of RSV. To investigate fluconazole gel pdf viewer the fundamental mechanisms by which both intralamellar and interlamellar relationships are disrupted by nuclear pressurization. Two reviewers independently identified articles, extracted data, assessed quality, and cross-checked the results.

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Gene selection can be cast as a feature selection problem in the context of pattern classification. The cataleptogenic effect of the epoxide was about 4 times as potent as the parent compound. Diet induces changes in plasma lipid profiles, and the plasma lipid profiles vary among different genetic backgrounds. Follow-up after radiotherapy was done by computed tomography scan every 6 months for 2 years cloridrato de tizanidina generico and yearly thereafter. Necroptosis: the release of damage-associated molecular patterns and its physiological relevance.

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The growth characteristics of multilocular ameloblastomas and the reaction of the surrounding tissues were studied by means of a histological examination of 31 surgical specimens. EM42 (human endometrial epithelial cell line) and primary endometrial epithelial cells were subjected to oxidative stress with minimally oxidized low density lipoprotein (mLDL). In conclusion, combined with an immunohistochemical analysis of the beta-catenin protein, this case provides the first evidence that genetic inactivation of the APC gene can play a significant role in zovanta 40 mg tabletas anticonceptivas the progression of sporadic HCC, probably by activating the Wnt/beta-catenin pathway. Masseter muscle hypertrophy (MMH) is most probably a congenital, genetically determined anomaly. The polygenic risk for bipolar disorder influences brain regional function relating to visual and default state processing of emotional information.

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Antidepressant response to FLU appears to be more dependent on 5-HT availability than that of DMI, suggesting that antidepressants mediate their therapeutic effects through different mechanisms. Apolipoprotein AIV requires cholecystokinin and vagal nerves to suppress food trileptal cost intake. We investigated whether a knowledge of infliximab serum concentration modifies physician decision and improves the control of disease activity in SpA.

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The level of labyrinthitis treatment prochlorperazine dosage thiobarbituric acid reacting substances and activities of superoxide dismutase, catalase, glutathione peroxidase, glutathione-S-transferase and GGT were increased and GSH level was decreased in pesticide poisoning. Evaluation of different glutathione S-transferase-tagged protein captures for screening E6/E6AP interaction inhibitors using AlphaScreen.

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He developed severe lactic acidosis, cardiac arrest, pancreatitis and hemolytic anemia which was treated with charcoal, sodium bicarbonate, early initiation of high volume continuous veno-venous hemofiltration and supportive therapy. Educational outreach to providers addresses the needs of patients with OUD and common co-occurring psychiatric and medical disorders. Tachykinins can be released in bone marrow as neurotransmitters from innervating fibers, and calutide cipla pharmaceuticals from resident bone marrow cells.

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Six patients presented with a history of tuberculosis in the family or with a tuberculosis primary infection. We calculated estimates of the knowledge and use of unauthorized HIV self-testing and assessed the associated factors by rare event logit regression models. These lesions demonstrated characteristic morphologic acnestop gel afrodita changes over a period of 8 weeks which were consistent with a diagnosis of self-resolving multifocal choroiditis.

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The sample was randomly divided into two, each group being sent the same questionnaire. As actively growing cells, these two strains tolerated regimes of pH, pressure, and temperature that were in most cases not tolerated under severe substrate limitation. Of 16 patients with kala-azar treated with sodium stibogluconate (0.1 ml/kg body weight a day), one died on the 12th day of treatment and nine were cured by gel e micosin a 30-day course, although two subsequently relapsed.

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Their dispersion in an aqueous solution was examined by phase contrast microscopy, neutron scattering, and solid state NMR. The possibility of osteoblastoma should be considered in cases of pain and swelling of phalanx, and if diagnosed, curettage and polymethylmethacrylate filling may be the treatment of choice. Psychological management of patients with amyotrophic lateral sclerosis (ALS) and their caregivers is a relatively recent concern, probably because there was previously a tendency to consider only physical functioning. The NS3-4A protease-helicase can directly bind to TERT, increase telomerase activity, and thus potentially influence telomere repair and host cell clindamycin-benzoyl perox gel reviews neoplastic behavior. Measurement error decreased from 0.011 mm with ordinary RSA to 0.004 with RSA digital measurement.

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Under operando conditions at 380 degrees C, we have found that Sb and V change their oxidation states depending sumycin syrup source on the C3H8/O2 ratio in the atmosphere. We compared the symptoms and laboratory findings of fever, vomiting, abdominal/flank pain, leukocyte count, serum C-reactive protein and procalcitonin levels with the results of the DMSA scan obtained within the first 72 h after referral in children who were diagnosed as having acute pyelonephritis.

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No significant effects of COMT genotype on neurocognitive performance were found. A rixadone risperidone withdrawal symptoms multilayer feed-forward neural network was trained with sets of experimental data relating concentration-time courses of plasma satiety hormones to Visual Analog Scales (VAS) scores. In most cases, mixed inflammation with debris and calcific material is present. This study showed that baseline CRP levels predicted the incidence of cardiovascular events and cancer-specific mortality over 7 to 8 years of follow-up. The architecture is being tested for implementing a prototype system able to coordinate the joint efforts of the professionals involved in managing patients affected by Acute Myeloid Leukemia.

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The low prevalence of the above mentioned polypeptides in tissues from mirror biopsies raises questions as to the extent of the disease far from the tumor area. On the other hand, expression of XRGSVI mRNA increased apparently at stage 14 gabalept capsule wardrobe and expression of three of other XRGS (III, IV, V) elevated between stage 25 and 40. To report the successful desensitization of a highly allergic patient with cystic fibrosis (CF) to inhaled aztreonam lysine using the novel approach of intravenous desensitization followed by full-dose inhaled therapy without any adverse reactions. Combined chemotherapy-radiotherapy study of small cell bronchial carcinoma: chemo-/radiotherapy vs radio-/chemotherapy The integration of quantitative genetics, paleontology, and neontology reveals genetic underpinnings of primate dental evolution.