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Combivir treats HIV infection. Do not miss any doses. Skipping doses can make it harder to treat HIV. Combivir is a prescription medication used to treat human immunodeficiency virus (HIV) infection. It is a single tablet containing 2 medications, lamivudine and zidovudine. They belong to a group of drugs called nucleoside reverse transcriptase inhibitors (NRTIs) which stop the virus from replicating. This medication comes in tablet form and is usually taken twice daily, with or without food. Common side effects include nausea, vomiting, headaches, and tiredness.

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Studies of the consequences of LMNA mutations in the skin cultured fibroblasts from the patients reveal abnormal nuclei in variable proportions, with dysmorphic nuclei exhibiting abnormal patterns of expression of B-type lamins and emerin. Additionally, we demonstrate that tru-gRNAs reduce the undesirable mutagenic effects of monomeric FokI-dCas9.

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Ten to 16 months have passed without any complications and all the patients are alive without any sign of tumor recurrence or metastatic involvement. We discuss what implies a preference for greater social distance towards the person in the vignette if identified as a male. Impact of the raising immunizations safely and effectively (RISE) program on healthcare worker influenza immunization rates in long term care settings. Our finding of an incidence rate of 1.65/100,000 person-years is in line with previously published studies.

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A new index (DHTi) for the net formation of dihydrotestosterone (DHT) in a specific tissue is presented. A partial smoke-free regulation in Spain was introduced on January 1, 2006, which was subsequently amended to introduce a comprehensive smoke-free policy from 2 January 2011 onward.

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There is a need for screening studies in order to select plant extracts or plant raw materials with strong antiradical activity which could be used as medicines or substances to protect food from oxidation. The slope-of-regression line, which was obtained from the relation between reciprocal serum creatinine concentration (1/Cr) and observation time, was expressed as a progression rate and was evaluated on an association with blood pressure level.

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The effect of dendrimer size on relaxation time, the conformation of spacers, and the size dependence of the dendrimer on molecular variables are discussed and compared with a Flory type theory. In contrast to K-RasV12 expression, epidermal growth factor receptor (EGFR) overexpression or mutation dramatically lowered the Casp9a/9b splice isoform ratio.

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A penicillin- and streptomycin-rich culture medium is effective in removing contaminating microbes. Signal transduction was investigated by immunoblot analysis of cell lysates. Progress must still be made in the study of calcified nodules and follicular tumors.

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To better understand the mechanism of larval development and diapause, we identified proteins with different expressions in the sixth instar of diapausing and non-diapausing larvae. We examined the clinical characteristics and predictive factors for mortality in coryneform bacteria bloodstream infection in hematological patients.

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Dual modes of natural selection on upstream open reading frames. Regulating MIA functions in vivo may provide a novel therapeutic strategy for metastatic melanoma disease. BAT activation detected by Dixon MRI in response to thermal challenges were correlated with glucose uptake of metabolically active BAT.

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The lesion was totally removed with a left subtemporal craniotomy. There was also no correlation between NCLs and other parameters examined. They presented as meningoencephalitis with extensive areas of haemorrhagic infarctions of frontoparietal lobes. Because bilirubin is a potent antioxidant, we examined the hypothesis that this bile pigment inhibits VCAM-1-dependent cellular events.

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The 21kDa protein can be rapidly released from the HeLa nuclei by micrococcal nuclease digestion. A mixed-methods investigation of successful aging among older women engaged in sports-based versus exercise-based leisure time physical activities. The Circozyme exhibits a stability comparable to PTO-modified DNAzymes without reduction of catalytic activity and specificity and may represent a promising tool for DNAzyme in vivo applications. Epidemiological evidence on the carcinogenic risk of air pollution.

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Analyses of other lipopolysaccharide salts support our hypothesis that many of the observed differences in the physical and pathological properties of lipopolysaccharide salts may simply be explained by the degree of charge neutralization. PARAMETERS AFFECTING THE ADSORPTION OF NATIVE ANTIGEN BY THE COMPLEX AND ITS SUBSEQUENT DESORPTION. Thus, pharmacological inhibition of autophagy may provide a novel therapeutic strategy for the treatment of stroke.

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AMH was predictive of both cycle cancellation and poor response with little inter-cycle variability. Massive weight loss after gastroplastic surgery is accompanied by an increase in circulating concentrations of the novel adipokine visfatin. In water samples artificially seeded with serovar bratislava, at least 10(3) cells could be analyzed by PCR-agarose gel electrophoresis and 1-10 cells by PCR-Southern blot hybridization.

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Post-IMRT 8th week, and more significantly, post-IMRT 6th month undetectable plasma EBV DNA were the only significant prognostic factors of 3-year survival endpoints. Most studies to date have been of severely depressed patients and this may give an unduly pessimistic picture.

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To undertake a systematic review and meta-analysis of all studies reporting the effect of MUL on the recovery of continence following RP. SGLT-2 inhibitors should only be used with great caution, extensive counseling, and close monitoring in the setting of type 1 diabetes. A thin film infrared technique is used to observe bands due to hydrogen-bonded and chemisorbed methoxymethylsilanes on fumed silica in the low-frequency region below 1300 cm(-1). The accelerated prenatal growth characteristic of Balaenoptera occurs during fetal, not embryonic, development. Localizing genes that are subject to recent positive selection is a major goal of evolutionary biology.

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Thus, the core 4E10 epitope was extended and modified to a WFX(I/L)(T/S)XX(L/I)W motif, where X does not play a major role in 4E10 binding and can be used to introduce helical-promoting constraints in the peptide epitope. Aftiphilin is a protein that was recently identified in database searches for proteins with motifs that interact with AP-1 and clathrin, but its function is unknown. Four hundred sixty consecutive upper urinary-tract procedures were performed utilizing the 7.5F actively deflectable, flexible ureteroscope. Acceptability was assessed by patient questionnaire and focus group analysis.

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Marked diurnal variation in the serum levels of some of these were detected. The algorithm reacts satisfactorily to random noise and breaks in the phase distribution. Circumocular pigmentation and incidence of ocular squamous cell tumors in Bos taurus and Bos indicus X Bos taurus cattle.

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Effects of macrolide antibiotics on bacteria-platelet interactions. It became evident that KLKs are involved in many physiological processes like semen liquefaction and skin desquamation. The Canadian Ophthalmological Society annual meeting and exhibition program. The cipher text is obtained by summing the weighted encryption key.

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Significant differences were found between cortisol sampling events and by junior or senior status. diversifolia extract, produced a delay in the latency to the SWS phase. Despite its importance in protein and mitochondrial homeostasis, mortalin tends to self-aggregate in vitro and in vivo, the later leads to mitochondrial biogenesis failure. Design, synthesis, and biological evaluation of cyclic peptidotriazoles derived from BPC194 as novel agents for plant protection. Exploratory factor analysis indicated that performance on all tasks could be accounted for by a single-factor model.

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With the increasing demands of applying protein synthesis to highly complex targets, examining these approaches becomes essential to achieve highly efficient synthesis. The rationale and potential for the reduction of oral malodour using Streptococcus salivarius probiotics. Among these glycoproteins, 50 were known to be N-linked glycoproteins and three novel glycopeptides from two predicted potential glycoproteins were discovered.

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The highest-scoring patches in many cases represent known ligand-binding sites for druggable targets, but not for difficult targets. Sost down-regulation by mechanical strain in human osteoblastic cells involves PGE2 signaling via EP4. The ability to accurately quantify ISA is not only expected to improve the reliability and reproducibility of lung function studies in injured-induced alveolar regeneration models, but also to promote mechanistic discoveries of multiple pulmonary diseases. In this way, more reliable, but also more expensive monitoring techniques can be used in preference to a higher number of low-cost but less reliable techniques. A patient is described in whom a profound and rapidly progressive dementia occurred in association with clinical features of amyotrophic lateral sclerosis.

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Reactivation of fetal hemoglobin (HbF) expression is an important therapeutic option in patients with hemoglobin disorders. US health insurance firm settles class action lawsuit brought by 900,000 doctors. In turn, hrpS is required for activity of the sigma factor homolog hrpL, which activates genes encoding TTSS structural and secreted proteins. To evaluate the accuracy of (13)carbon urea breath testing for H. We describe two pairs of sisters as well as a mother and daughter presenting with idiopathic subglottic stenosis.

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Pneumonia is the leading infectious cause of under-5 mortality in sub-Saharan Africa. ENB with or without r-EBUS is a safe, efficient, and easily applied method for sampling of peripheral lung lesions, with high diagnostic yield independent of lesion size and location.

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Tasks measuring phonological awareness, lexical access, and syntactic awareness were administered when the children entered school in kindergarten at age 5. A small push-pull molecule involving a diphenylamine substituted by an oligo-oxyethylene chain is described. Unlike Asian non-human primates, chronically SIV-infected African non-human primates (NHP) display a non-pathogenic disease course. Using this approach we have determined the limiting rate constant (1770 s-1 for substrate-free heme domain) for formation of the FeII-CO complex.

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A benzothiadiazine derivative and methylprednisolone are novel and selective activators of transient receptor potential canonical 5 (TRPC5) channels. Vancomycin-resistant enterococci from nosocomial, community, and animal sources in the United States.

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Congenital melanocytic nevi frequently harbor NRAS mutations but no BRAF mutations. 2-Oxoglutarate downregulates expression of vascular endothelial growth factor and erythropoietin through decreasing hypoxia-inducible factor-1alpha and inhibits angiogenesis. These changes involved elevated levels of ketone compounds including 3-hydroxybutyrate, acetoacetate, and acetone, some amino acids including asparagine, glutamate, threonine, and phenylalanine, glycoproteins and lipoproteins including N-acetylglycoprotein, LDL and VLDL, and some metabolites that have been shown to contribute to mutagenicity and cancer promotion such as deoxyguanosine and cytidine. The mechanosensitive channel of large conductance (MscL) from E. The outer surface of the myelin sheath was well visualized in electron micrographs of replicas and the distribution of its cytoplasm-containing portions could be analysed.

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Populations connected by rotational sheep grazing showed significantly weaker SGS and higher genetic diversity than populations in ungrazed grasslands. Targeting advanced glycation with pharmaceutical agents: where are we now? The results are analyzed in terms of a simple Flory-type theory of the collapse transition. To review the clinical features, neurobiological correlates and treatment of pathological laughing and crying.

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Most research has been focused on the controlled release of single drugs to demonstrate the therapeutic feasibility. These cost savings were also significant in the subset of patients who had persistent hypertension and diabetes after surgery. Terminal syringomyelia communicating with a spinal dermal sinus. The breast cancer ET is related to the changes in BS and BC in premenopausal women. The expression of ILT4 could be up-regulated by IL-10 both at the transcriptional and translational level.

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Simultaneously, fluorescence emission shifts from a weak band initially at longer wavelength to another strong one finally at shorter wavelength. We investigated the relationship between total fat intake and other nutrient intake using INTERLIPID/ INTERMAP data on Japanese people living in Japan. Seroprevalence of Neospora caninum infection in farmed sika deer (Cervus nippon) in China. Lumbosacral epiduroscopy is technically feasible in standing horses and may become a valuable diagnostic tool in horses with caudal back or limb pain of unknown origin.

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The model consists of a coupled system of second order PDEs describing the evolution of CXCL-12 and PTHrP, an ODE of logistic type to model the Osteoblasts density and an extra equation for each cancer cell. This consisted of the vascularized femoral bone/bone marrow transplant. IGF-I is recognized as an important neuroprotective factor against cerebral hypoxic insult. There were insufficient data regarding vaginal surgery prophylaxis. The full guideline document covers the entire process of population-based screening.

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This research investigated whether regular spatial orienting sequences can be learned implicitly and independently of response requirements. The pH of ovarian fluid remained constant at 8.5 during in vivo ovarian follicle maturation and ovulation. Six databases were systematically searched for studies on the QOL outcomes of DSME interventions for adolescents with T1DM. The selective blockade of both nerves showed satisfactory analgesia, with the advantage of providing motor block restricted to the shoulder. Visual acuity, intraocular pressure, and anterior segment examination were normal.

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Another dosing consideration involves the effect of long-term alcohol abuse on drug metabolism (e.g., when treating alcohol-dependent patients for comorbid psychiatric disorders). Using the Kaplan-Meier estimator, we conducted a monocentric, retrospective, observational, open-label study to evaluate LCM retention rates in patients with IDs and drug-resistant epilepsy. Importance of hospital pharmacies to Danish pharmacy in the past 50 years Phenolsulfonphthalein (PSP), as a marker substance, was intraperitoneally or intravenously injected into MGO-treated rats.

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MAb Pine-1 (2D11G1, IgG1 with kappa light chain) reacted to all 43 pineapple/water strains and some reference strains (D. Guideline for Reversal of Antithrombotics in Intracranial Hemorrhage: Executive Summary.

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Severe alterations of red blood cells from the vessels of colorectal tumors. When injected by the intraperitoneal route, the fri mutant demonstrated a reduced capacity to proliferate in the organs of infected mice relative to the wild-type, whereas when the bacteria were supplied intravenously this effect was mitigated. Stressors increased plasma ACTH by 2.5- to 5-fold in control rats.

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We did a review of the medical literature and of our series of patients treated between 1996 and 2004. An approximately three fold increase of plasma dopamine sulfate concentrations following banana ingestion did not result in increased dopamine sulfate concentrations in cerebrospinal fluid. In vitro controlled release of vinpocetine-cyclodextrin-tartaric acid multicomponent complexes from HPMC swellable tablets.

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Here we show that different proportions of GABA(A) and GABA(C) receptor-mediated inhibition determined the kinetics of GABAergic presynaptic inhibition across different BC classes. In addition, the versatility of these synthetic mimics provides the opportunity to discover analogs with superior properties compared with their native sequences. This short review deals with our investigations in neuroendocrine tumors (NETs) with antibodies against defined epitopes of chromogranins (Cgs) A and B and secretogranins (Sgs) II and III. CNV activity, RTs and clinical patterns progressively improved also in 2 PAD patients while in the 3rd they remained nearly unchanged or minimally worse during the 6-month treatment. The dogs were treated with various anthelmintics of well established efficacy (pyrantel, nitroscanate, mebendazole, piperazine) 20 dpi.

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A retrospective data analysis was done of all the cases diagnosed as STIs during a 33 year period from 1974 to 2006. To analyze determinants of utility in CHF and drivers of change over 1 year in a large sample from clinical practice. Antibodies to HCV were detected employing a commercially available second-generation enzyme immunoassay (EIA, Abbott II). A complete remission of the disease after an administration of bortezomib (Velcade)-based regimen in a long-term clodronate (Bonefos)-treated patient with relapsed multiple myeloma is radiographically apparent by clear healing signs of the osteolytic bone lesion. The importance of the diseasome and network medicine concepts in the study of comorbidity is emphasized.

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Various mutations causing OCA in man, mouse, rabbit and cattle have been identified throughout the Tyrosinase gene including nonsense, missense, frameshift and splice site alterations. PEG, PED PEJ and DPEJ are easily handled, effective and safe, and may be widely used in clinical practice. We objectively assessed surface structural changes of the hippocampus in mesial temporal sclerosis (MTS) and assessed the ability of large-deformation high-dimensional mapping (HDM-LD) to demonstrate hippocampal surface symmetry and predict group classification of MTS in right and left MTS groups compared with control subjects.

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Niobium-Doped Hydroxyapatite Bioceramics: Synthesis, Characterization and In Vitro Cytocompatibility. THE POSSIBILITY OF CONTROLLING THE GROWTH OF YEASTS BY BACTERIA OF THE contiflo xl sexual side effects treatment ORAL MUCOSA Taking control: Complementary and alternative medicine in diabetes and cardiovascular disease management.

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Our data suggest that reduction of cellular defense against oxidative stress by Nrf2 inhibition may be a plausible mechanism of OTA nephrotoxicity and carcinogenicity. to characterize population and to know mecir vs mcenroe vs borg how and where they are acting, if there is legislation applicability on their practice. These findings implicate a shared molecular basis for the developmental arrest and latent myopathy of left and right ventricles, respectively. Chemical tailoring of fullerene acceptors: synthesis, structures and electrochemical properties of perfluoroisopropylfullerenes. Patients with BRAF wild-type tumors and BRAFv600 mutated tumors can be treated with immunotherapy i.e.

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The model assumes that contemporary implicit measures tap quick evaluative associations, whereas explicit measures also consider the perceived validity of these associations (and other factors). Some could be biomarkers that need to be individually confirmed by correlation with clinical parameters and validation by other methods on larger cohorts of patients. The principle of SAW technology is based on the piezoelectric properties of the sensors, so as to binding events and their accompanied mass increase at the sensor surface are detectable by a change in the oscillation of the surface infezione dente augmentin dose acoustic wave. 20 hepatectomized patients, both cirrhotic and noncirrhotic, were studied for the postoperative changes in the arterial blood ketone body ratio and standard liver function tests. Current perspectives on management of co-morbid depression in COPD.

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With speech competition, elderly listeners exhibited significantly larger reductions in P2 amplitude than did young listeners. An electronic literature search actiq dosage forms of spironolactone was employed to look for published randomised controlled trials, a controlled trials or time interventions containing research questions regarding the prevention of lateral ankle ligament injuries.

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Extraesophageal reflux disease sulfa allergy and uroxatral often requires diagnosis and treatment by a phoniatry or ear, nose and throat specialist. Knowledge about effects of alcohol acting contains 11 questions. Describe the local morphological response of the articular-epiphyseal cartilage complex to surgical stab incision in the distal femur of foals, with emphasis on the relationship between growth cartilage injury, enchondral ossification, and repair. Eventually, though, minority carrier conduction becomes significant and ZT decreases above a certain temperature.

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In contrast to the antihypertensive effect of NaCl reduction, from a clinical scientific perspective a positive effect on cardiovascular mortality has not been sufficiently demonstrated. It has little donor site morbidity in spite of providing a large surface area of full-thickness skin. Molecular clock components in Arabidopsis thaliana showed complex, photoperiod-dependent regulation, which was analysed by comparison with three contrasting models. Evaluation of the human relevance of the proposed MOA of formaldehyde in rodents is restricted albendazole 200 mg indicaciones de afumix by human data limitations, although the key events are plausible.

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Investigations of the lymphocytes of patients with lupus erythematodes disseminatus by means of the lymphocyte transformation test and the determination of the B-cells with the help of the gapridol gabapentina 300 mg direct immune peroxidase technique refer to the close pathogenetic connections of cellular and humoral immune reactions in this disease. Analytical chemistry, toxicology, epidemiology and health impact assessment of melamine in infant formula: recent progress and developments.

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Further, our data suggest that this asymmetric interaction acts cooperatively with the interaction between dimerization elements to promote HAP1 dimerization, and locks HAP1-DNA complexes in a stable, dimeric conformation. Safety of heavy equipment operators in particular is a major concern in excavation that needs to be addressed. Furthermore, some reports have mentioned that endothelial cells were positive for VEGF antibody but have not evaluated its significance. Research using daily designs has shown that venla savikuja 2015 best daily stressors (i.e., conflict, school/work demands) are associated with alcohol use, and that the strength of within-person links between stressors and alcohol use differs from person to person. Due to the high prevalence of malnutrition and the rapid development of anorexia-cachexia-syndrome, early nutritional intervention is crucial and supported by clinical data.

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The results suggest that congenital cerebellar dysmorphology in spina bifida does not impair motor skill learning as measured by acquisition and retention of the mirror drawing task. Among maternally separated groups, the percentage of time spent in the open arms amfebutamone hydrochloride 25 was significantly increased in the HT7 acupuncture group, but not the ST36 acupuncture group, compared to MS group.

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Data were extracted and methodological quality was assessed by two reviewers using the Critical Review Form-Quantitative Studies. To assess and compare, for the first time, the quantity finalop ou finasteride generic and quality of dental undergraduate teaching in conscious sedation in the dental schools of the UK and Ireland.

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How the formation of the early axon scaffold augmentin injection uses is controlled at the molecular level is unclear. Demonstration of early efficacy results of the delayed-release combination of doxylamine-pyridoxine for the treatment of nausea and vomiting of pregnancy. A model in which pp25 connects a type of serpin (serine protease inhibitor), the only pp25-binding protein detected in the cytoplasm, to the endoplasmic reticulum through two serine clusters is proposed to explain a possible function of this protein. Furazolidone is a bactericidal agent used to treat infectious enteropathies. In addition, we retrospectively reviewed the notes of patients presenting with intractable epilepsy in which we had found POLG mutations.

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